by jo.dobson@kcl.ac.uk | Dec 4, 2025
Rapid advances in omics technologies, coupled with major improvements in computational and analytical tools, have enabled the generation of high-quality, cost-efficient multi-omics data that are now driving the emergence of precision health and precision medicine...
by jo.dobson@kcl.ac.uk | Dec 3, 2025
Background:Advances in wearable and smartphone technologies have opened new possibilities for continuous, real-world monitoring of health and behaviour. While numerous studies have explored digital biomarkers within specific conditions such as depression or epilepsy,...
by jo.dobson@kcl.ac.uk | Dec 3, 2025
Background:Patient recruitment is a major challenge in clinical trials (CT) and the most common cause of trial discontinuation. Over half (55%) of publicly funded CTs fail to reach their recruitment targets [4], leading to incomplete studies, increased costs when...
by jo.dobson@kcl.ac.uk | Dec 3, 2025
Background Schizophrenia causes substantial personal and societal burden, with about one-third of patients developing treatment-resistant schizophrenia (TRS), defined as non-response to two adequate antipsychotic trials. Clozapine is the only proven TRS treatment, yet...
