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AI-Driven Retrobiosynthesis for Mechanistic Discovery in Cancer and Precision Medicine

by jo.dobson@kcl.ac.uk | Dec 4, 2025

Rapid advances in omics technologies, coupled with major improvements in computational and analytical tools, have enabled the generation of high-quality, cost-efficient multi-omics data that are now driving the emergence of precision health and precision medicine...

AI-Driven Cohort Identification: Multi-Agent System for Neurology Clinical Trial Recruitment

by jo.dobson@kcl.ac.uk | Dec 3, 2025

Background:Patient recruitment is a major challenge in clinical trials (CT) and the most common cause of trial discontinuation. Over half (55%) of publicly funded CTs fail to reach their recruitment targets [4], leading to incomplete studies, increased costs when...

A multimodal data-driven approach to sustainable healthcare – leveraging community volunteering support to improve patients’ mental health outcomes

by jo.dobson@kcl.ac.uk | Dec 3, 2025

Background:Volunteering support is increasingly recognised as a valuable public health intervention for improving mental health outcomes, but its broader population-level impact remains under-researched. This project seeks to investigate the effects of volunteering on...

GenAI for Early Detection of Treatment Resistance and Fair Access to Clozapine in Schizophrenia

by jo.dobson@kcl.ac.uk | Dec 3, 2025

Background Schizophrenia causes substantial personal and societal burden, with about one-third of patients developing treatment-resistant schizophrenia (TRS), defined as non-response to two adequate antipsychotic trials. Clozapine is the only proven TRS treatment, yet...

Integrative analysis of colon tissue multi-omics with electronic health record data to investigate the role of host-microbiome interactions in human health

by luke | Dec 1, 2025

1. Background The human colon is home to trillions of microorganisms, or the gut microbiota, which affect the health of the host through complex interactions with the host. Much research is focused on identifying host-microbiome interactions in both health and...
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  • LifeArc’s Chris Tomlinson hosts our February Seminar Series
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  • John Jumper, PhD, from Google’s DeepMind talks about AlphaFold2

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